CLONAZOLAM

Clonazolam Summary

IUPAC Name: 6-(2-Chlorophenyl)-1-methyl-8-nitro-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine

Molecular Weight: 353.762

Formula: C17H12ClN5O2

InChI: InChI=1S/C17H12ClN5O2/c1-10-20-21-16-9-19-17(12-4-2-3-5-14(12)18)13-8-11(23(24)25)6-7-15(13)22(10)16/h2-8H,9H2,1H3

InChI Key: XJRGLCAWBRZUFC-UHFFFAOYSA-N

SMILES: Clc1ccccc1C1=NCc2n(c3c1cc(cc3)N(=O)=O)c(nn2)C

Links:

Similar Compounds:

NORFLURAZEPAM
DICLAZEPAM
NITRAZOLAM
METHYL-CLONAZEPAM
3-HYDROXYPHENAZEPAM
BROMAZOLAM
FLUNITRAZOLAM
FLUALPRAZOLAM
SL-164
PAGOCLONE

References:

Manchester, KR; Lomas, EC; Waters, L; Dempsey, FC; Maskell, PD. The emergence of new psychoactive substance (NPS) benzodiazepines: A review. Drug Test. Analysis, 1 Jan 2018, 10 (1), 37-53. 713 kB. https://doi.org/10.1002/dta.2211 #2C

Dowling, G; Kavanagh, PV; Eckhardt, H; Twamley, B; Hessman, G; McLaughlin, G; Brien, JO; Brandt, SD. An approach to shortening the timeframe between the emergence of new compounds on the drugs market and the availability of reference standards: the microscale syntheses of nitrazolam and clonazolam, for use as reference materials, utilizing polymer support. Drug Test. Analysis, 1 Jul 2018, 10 (7), 1198-1208. 728 kB. https://doi.org/10.1002/dta.2383

EMCDDA. New drugs in Europe, 2015, European Monitoring Centre for Drugs and Drug Addiction, Lisbon, 1 May 2016. 1.0 MB. #4

Huppertz, LM; Bisel, P; Westphal, F; Franz, F; Auwärter, V; Moosmann, B. Characterization of the four designer benzodiazepines clonazolam, deschloroetizolam, flubromazolam, and meclonazepam, and identification of their in vitro metabolites. Forensic Toxicol., 1 Jul 2015, 33 (2), 388–395. 870 kB. https://doi.org/10.1007/s11419-015-0277-6 #1

Bergstrand, MP; Helander, A; Hansson, T; Beck, O. Detectability of designer benzodiazepines in CEDIA, EMIT II Plus, HEIA, and KIMS II immunochemical screening assays. Drug Test. Analysis, 1 Apr 2017, 9 (4), 640-645. 522 kB. https://doi.org/10.1002/dta.2003

Moosmann, B; King, LA; Auwärter, V. Designer benzodiazepines: A new challenge. World Psychiatry, 1 May 2015, 14 (2), 248-248. 49 kB. https://doi.org/10.1002/wps.20236

Moosmann, B; Auwärter, V. Designer benzodiazepines: Another class of new psychoactive substances. In New Psychoactive Substances : Pharmacology, Clinical, Forensic and Analytical Toxicology; Maurer, HH; Brandt, SD, Eds., Springer, Berlin, Heidelberg, 1 Jan 2018; pp 383-410. 497 kB. https://doi.org/10.1007/164_2018_154 #Clonazolam