BROMAZOLAM

Bromazolam Summary

Bromazolam (XLI-268) is a benzodiazepine derivative which was first synthesized in 1976, but was never marketed.^[1] It has subsequently been sold as a designer drug, first being definitively identified by the EMCDDA in Sweden in 2016.^[2] It is the bromo instead of chloro analogue of alprazolam, and has similar sedative and anxiolytic effects to other diazepines (etizolam, flualprazolam, flubromazolam, etc.).^[3][4]

IUPAC Name: 8-Bromo-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine

Molecular Weight: 353.216

Formula: C17H13BrN4

InChI: InChI=1S/C17H13BrN4/c1-11-20-21-16-10-19-17(12-5-3-2-4-6-12)14-9-13(18)7-8-15(14)22(11)16/h2-9H,10H2,1H3

InChI Key: KCEIOBKDDQAYCM-UHFFFAOYSA-N

SMILES: Brc1ccc2c(c1)C(=NCc1n2c(C)nn1)c1ccccc1

Links: 

ChemSpider 19871738
PubChem 12562546
Wikipedia Bromazolam

Similar Compounds: 

NORFLURAZEPAM
DICLAZEPAM
NITRAZOLAM
METHYL-CLONAZEPAM
3-HYDROXYPHENAZEPAM
FLUNITRAZOLAM
FLUALPRAZOLAM
CLONAZOLAM
SL-164
PAGOCLONE

References: 

Manchester, KR; Lomas, EC; Waters, L; Dempsey, FC; Maskell, PD. The emergence of new psychoactive substance (NPS) benzodiazepines: A review. Drug Test. Analysis, 1 Jan 2018, 10 (1), 37-53. 713 kB. https://doi.org/10.1002/dta.2211 #2C

EMCDDA. New drugs in Europe, 2016, European Monitoring Centre for Drugs and Drug Addiction, Lisbon, 1 May 2017. 489 kB. #59

Moosmann, B; Auwärter, V. Designer benzodiazepines: Another class of new psychoactive substances. In New Psychoactive Substances : Pharmacology, Clinical, Forensic and Analytical Toxicology; Maurer, HH; Brandt, SD, Eds., Springer, Berlin, Heidelberg, 1 Jan 2018; pp 383-410. 497 kB. https://doi.org/10.1007/164_2018_154 #Bromazolam